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Introduction by Daniel Clauw 00:00:00 Title Slide 00:02:02 Problems for Clinician-Scientists: endangered species 00:02:42 -- Crisis in Clinical Research 00:03:10 -- Investigator-initiated applications 00:03:20 -- The four P's 00:03:38 -- number of first-time MD applicants 00:04:02 -- graph: decreasing MD's 00:04:15 -- Four key challenges for U.S. 00:04:26 -- Translating Biomedical Research 00:05:48 The Promise of Basic Research 00:06:25 Delivering on the Promise 00:06:59 Problems for Clinician-Scientists: Gloom & Doom? 00:07:23 Eugene P. Orringer 00:07:56 -- Mentors & Role Models 00:08:23 -- John C. Parker, MD 00:09:33 -- Fellowship Training 00:09:39 -- Initial NIH Funding 00:10:12 -- Subsequent NIH Funding 00:10:12 -- Evolution as a Clinical Investigator 00:10:23 The UNC Sickle Cell Program 00:11:16 -- Wendell F. Rosse, MD 00:12:13 -- long-standing collaboration 00:12:27 -- joint efforts with Duke 00:12:39 -- 1st joint Duke-UNC application 00:13:02 General Clinical Research Center 00:13:25 -- Program Director 00:14:24 UNC MD-PhD Program 00:15:36 -- graph: UNC MD-PhD's 1995 to Present 00:16:53 -- The current year (2003) 00:17:06 Institutional Philosophy - I 00:17:44 Executive Associate Dean 00:18:56 School of Medecine UNC-Chapel Hill 00:19:32 -- New Chairs & Center Directors 00:19:47 Institutional Philosophy - II 00:20:28 Executive Associate Dean 00:20:59 NIH Directors Panel 00:21:34 Clinical Research Enhancement Act 00:22:09 Eugene P. Orringer 00:23:00 UNC-CH School of Medicine 00:23:13 Office of Research and Faculty Development 00:24:00 -- multidisciplinary proposals 00:24:17 NIH Support 00:25:11 Office of Research & Faculty Development 00:25:45 -- Work with junior faculty 00:26:37 -- the past 3+ years 00:27:28 K23 - Patient Oriented Research CDA 00:28:00 Total number of K23 Awards 00:28:13 NIH Support to UNC 00:28:30 Total NIH Support to the Extramural Community 00:28:55 Total NIH's $'s vs. K23 Awards 00:29:27 Office of Research & Development: leadership role 00:29:52 UNC-Chapel Hill Medical Student Research Programs 00:30:16 Medical Student Research 00:30:26 Contributions to Medical Student Research 00:31:06 Doris Duke Medical Student Clinical Research Program 00:31:38 Contributions to Medical Student Research 00:32:43 UNC-Chapel Hill: Career Development 00:33:31 School of Medicine: passionate commitment 00:33:34 -- Foster Development of Clinician-Scientists 00:33:48 K30 - Clinical Research Curriculum 00:33:55 -- Most K30 Programs 00:34:09 -- Broad-Based Program 00:34:40 -- Structure 00:34:55 -- Status of the Trainees 00:36:10 Programs for Career Development 00:36:39 K12 Award 00:36:41 The BIRCWH Program 00:36:59 UNC BIRCWH Program 00:37:12 -- Scholars and Associates 00:37:37 BIRCWH Scholar 00:37:43 BIRCWH Associate 00:37:48 UNC BIRCWH Program 00:38:03 K12 Awards 00:38:14 -- Example 00:38:41 -- Status of the Trainees 00:38:56 K12 - MCRSP 00:39:30 -- Structure of UNC's K12 Application 00:40:08 -- quality of initial candidates 00:40:20 MCP Scholars 00:40:43 -- Advisory Committee 00:41:46 -- Total # of awardees in the program 00:42:20 -- increasing diversity 00:43:18 -- Funding Status of the Scholars 00:43:39 Center of Excellence - HRSA 00:44:17 New Career Opportunities for Clinician/Scientists 00:44:59 Photograph 00:45:40 Audience Question: clinical research nationally as opposed to UNC 00:46:20 Audience Question: attracting appropriate candidates 00:50:19 Audience Question: attracting candidates nationally 00:50:56 Audience Question: does the institution value clinical research? 00:52:39 Audience Question: advice for "translational researchers" 00:55:28