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JUMP DIRECTLY TO SLIDE Introduction by Daniel Clauw Title Slide Problems for Clinician-Scientists: endangered species -- Crisis in Clinical Research -- Investigator-initiated applications -- The four P's -- number of first-time MD applicants -- graph: decreasing MD's -- Four key challenges for U.S. -- Translating Biomedical Research The Promise of Basic Research Delivering on the Promise Problems for Clinician-Scientists: Gloom & Doom? Eugene P. Orringer -- Mentors & Role Models -- John C. Parker, MD -- Fellowship Training -- Initial NIH Funding -- Subsequent NIH Funding -- Evolution as a Clinical Investigator The UNC Sickle Cell Program -- Wendell F. Rosse, MD -- long-standing collaboration -- joint efforts with Duke -- 1st joint Duke-UNC application General Clinical Research Center -- Program Director UNC MD-PhD Program -- graph: UNC MD-PhD's 1995 to Present -- The current year (2003) Institutional Philosophy - I Executive Associate Dean School of Medecine UNC-Chapel Hill -- New Chairs & Center Directors Institutional Philosophy - II Executive Associate Dean NIH Directors Panel Clinical Research Enhancement Act Eugene P. Orringer UNC-CH School of Medicine Office of Research and Faculty Development -- multidisciplinary proposals NIH Support Office of Research & Faculty Development -- Work with junior faculty -- the past 3+ years K23 - Patient Oriented Research CDA Total number of K23 Awards NIH Support to UNC Total NIH Support to the Extramural Community Total NIH's $'s vs. K23 Awards Office of Research & Development: leadership role UNC-Chapel Hill Medical Student Research Programs Medical Student Research Contributions to Medical Student Research Doris Duke Medical Student Clinical Research Program Contributions to Medical Student Research UNC-Chapel Hill: Career Development School of Medicine: passionate commitment -- Foster Development of Clinician-Scientists K30 - Clinical Research Curriculum -- Most K30 Programs -- Broad-Based Program -- Structure -- Status of the Trainees Programs for Career Development K12 Award The BIRCWH Program UNC BIRCWH Program -- Scholars and Associates BIRCWH Scholar BIRCWH Associate UNC BIRCWH Program K12 Awards -- Example -- Status of the Trainees K12 - MCRSP -- Structure of UNC's K12 Application -- quality of initial candidates MCP Scholars -- Advisory Committee -- Total # of awardees in the program -- increasing diversity -- Funding Status of the Scholars Center of Excellence - HRSA New Career Opportunities for Clinician/Scientists Photograph Audience Question: clinical research nationally as opposed to UNC Audience Question: attracting appropriate candidates Audience Question: attracting candidates nationally Audience Question: does the institution value clinical research? Audience Question: advice for "translational researchers"        synchronize video with current slide